ONE-POT SYNTHESIS OF PYRIMIDINE-5-CARBOXALDEHYDE AND ETHYL PYRIMIDINE-5-CARBOXYLATE BY UTILIZING PYRIMIDIN-5-YL-LITHIUM

Authors
RHO TY ABUH YF
Citation
Ty. Rho et Yf. Abuh, ONE-POT SYNTHESIS OF PYRIMIDINE-5-CARBOXALDEHYDE AND ETHYL PYRIMIDINE-5-CARBOXYLATE BY UTILIZING PYRIMIDIN-5-YL-LITHIUM, Synthetic communications, 24(2), 1994, pp. 253-256
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
24
Issue
2
Year of publication
1994
Pages
253 - 256
Database
ISI
SICI code
0039-7911(1994)24:2<253:OSOPAE>2.0.ZU;2-V
Abstract
Pyrimidine-5-carboxaldehyde was prepared in a one-pot reaction from 5- bromo-pyrimidine via metal halogen exchange. Pyrimidin-5-yl-lithium re acted with formate ester and ethyl cyanoformate, forming respectively the aldehyde and carboxy ethyl ester.