PRIMARY ANORECTAL MALIGNANT-MELANOMA - RE PORT OF A CASE AND REVIEW OF THE LITERATURE

A 50-year old man developed a nonpigmented malignant melanoma in the a norectal area. The diagnosis was established by a biopsy. The histolog ic diagnosis oi this highly malignant tumor can be difficult in nonpig mented forms, and can benefit from the use oi PS 100 and HMB 45 as imm unological markers. Although surgery is the mainstay oi management, th e best method is not agreed on, and the prognosis seems more closely d ependent on the stage ct the disease than on the type ct surgical proc edure performed. The role of radiation therapy and chemotherapy needs to he evaluated.