KINETICS OF OXIDATION OF CAFFEINE BY BROMAMINE-B IN HCL MEDIUM

Kinetics of oxidation of caffeine by sodium N-bromobenzenesulphonamide (bromamine-B; BAB) in ACI medium have been studied at 288 IG The rate shows a first order dependence on [BAB], fractional orders in [H+] an d [CP-] and is independent of[caffeine], Addition of the reaction prod uct, benzenesulphonamide and variation of ionic strength of the medium have no effect on rate. A decrease of the dielectric constant of the medium decreased the rate constant. The solvent isotope effect has bee n studied in D2O medium Activation parameters have been evaluated from the Arrhenius plots. Mechanisms proposed and the derived rate laws ar e in agreement with the observed kinetics.