Ne. Sviderskaya et al., SPATIAL-ORGANIZATION OF HUMAN EEG DURING KETAMINE-ALTERED STATE OF CONSCIOUSNESS, Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 48(2), 1998, pp. 195-205
Spatial organization of human EEG was studied by means of topographic
mapping methods with the multiparametric data estimations in the state
altered by ketamine in terms of the concept of coherent structures of
brain electrical activity. Two main features of the altered state of
consciousness were reflected in the opposite shifts: an increase in th
e spatial synchronization in the left hemisphere (especially, in the p
osterior area) and its decrease in the left frontal and right temporal
one. The obtained data are discussed from the viewpoint of dissociati
ve effects of ketamine at the neurochemical and neurophysiological lev
els.