FINE-NEEDLE ASPIRATION CYTOLOGY OF A SOLID PAPILLARY CARCINOMA OF THEBREAST - A CASE-REPORT WITH IMMUNOHISTOCHEMICAL STUDIES

BACKGROUND: Solid papillary carcinoma of the breast was recently descr ibed. This tumor displays distinctive clinical and morphologic feature s. It is an intraductal papillary carcinoma frequently associated with mucinous carcinoma and infiltrating ductal carcinoma not otherwise sp ecified. CASE: Fine needle aspiration cytology (FNAC) of a solid papil lary carcinoma of the right breast in an 82-year-old female, demonstra ted a cellular specimen of dis-cohesive, small, uniform and ovoid tumo r cells, with occasional loose clusters. The cytoplasm was abundant an d finely granular. The nuclei were round, without marked atypia. The n ucleoli were inconspicuous. Scant mucinous material was present. The d iagnosis was confirmed histologically and immunohistochemically. CONCL USION: The cytologic aspects of solid papillary carcinoma of the breas t suggest It carcinoma with endocrine differentiation and a weak mucin ous component.