There is a causal relationship between diabetic foot ulceration, eleva
ted plantar pressure, and severe sensory neuropathy. Cushioned footwea
r intended to relieve plantar pressure is well established for prevent
ion and healing of planter ulcers. The aim of the present study was to
investigate whether pressure relief by means of a running shoe with o
ptimized forefoot pressure damping is comparable to that of a custom-m
ade soft insole placed into an in-depth shoe. The in-shoe pressures we
re compared to an in-depth shoe with the original cork insole and with
a leather-soled Oxford shoe. The maximum reduction of plantar pressur
e in the running shoe was 47% under the 2nd and 3rd metatarsal heads,
29% at the first metatarsal head, and 32% at the great toe in comparis
on to the Oxford shoe. This was surpassed only by the custom-made inso
le, which reduced pressures at the metatarsal heads by 50%. The specia
lly designed running shoe yielded the same pressure relief at the cent
ral metatarsal heads as the custom-made insole. Such shoes are likely
to be very useful in preventing diabetic foot ulceration in high-risk
patients as a comparatively affordable and immediately available devic
e. (C) 1998 John Wiley & Sons, Ltd.