MANDIBULO-FACIAL DYSOSTOSIS - COMPARISON STUDY OF A NEONATE WITH MANDIBULO-FACIAL DYSOSTOSIS AND A NORMAL NEONATE

Mandibulo-facial dysostosis (MFD) is a malformative syndrome with auto somal dominant transmission and variable expressivity that mainly affe cts derivatives of the first and second branchial arches. The subsurfa ce anatomy of this condition is still partly unexplored since there ha ve been only four reported dissections of MFD. A detailed dissection o f the head and neck of a neonate with MFD is described and compared wi th a normal neonate. Theories of the pathogenesis are discussed on the basis of these observations.