EARLY CAROTID ENDARTERECTOMY AFTER NONDISABLING ISCHEMIC STROKE - ADEQUATE THERAPEUTIC OPTION IN SELECTED PATIENTS

Objective: To evaluate neurological outcome and long-term results of e arly carotid endarterectomy (CEA) after non-disabling stroke. Material s: Retrospective study between 1980 and 1995 of 56 patients undergoing CEA within 4 weeks of a transient (n=15) or a permanent non-disabling (n=41) ischaemic stroke. Methods: Analyses of preoperative cerebral C T imaging, neurological outcome (mod. Rankin-scale) and long-term resu lts (life-table analyses according to Kaplan-Meier). Results: Incidenc e of early CEA increased from 1.7% (27 out of 1636) in the period 1980 -1993 to 7.8% (29 out of 374) between 1994 and 1995. CEA was indicated after a neurological plateau phase was established (median interval 1 4 days). Fifty-seven per cent of the CEA patients had a minor ischaemi c infarction (area < 2 cm), 18% showed a large territorial ischaemic i nfarction (area 2-5 cm) in cerebral CT imaging. Two patients deteriora ted postoperatively (minor stroke rate 4%) but no major stroke or deat h occurred. Life-table probability of stroke-free survival (mean follo w-up 42.7 months) was 94%, 90% and 84%, respectively, after 1, 2, and 5 years. Kaplan-Meier survival rates were 96%, 91% and 86% after 1, 2 and 5 years. Conclusions: Early CEA after non-disabling stroke is a sa fe procedure in selected patients.