Endoluminal therapy is widespread among different clinical specialitie
s. Endoluminal therapy of gastrointestinal disease, endovascular thera
py of stenoses, and transurethral resection of the prostate are only t
hree examples from this diversified medical field. Notwithstanding the
impressive technical possibilities offered by contemporary products,
technological advances will have a considerable impact on the further
development of endoluminal therapy. New technologies, such as microsys
tem technology, will bring about significant advances in both function
ality and performance of endoluminal systems. Miniaturized robotic com
ponents and sensor systems for analysis of tissues in situ could form
part of advanced devices applied, for example, to local tumour surgery
. This article describes, in brief, a scenario of an endoluminal manip
ulator system and its technological platform.