NICOTINES OPIOID AND ANTI-OPIOID INTERACTIONS - PROPOSED ROLE IN SMOKING-BEHAVIOR

Authors
ACETO MD SCATES SM JI Z BOWMAN ER
Citation
Md. Aceto et al., NICOTINES OPIOID AND ANTI-OPIOID INTERACTIONS - PROPOSED ROLE IN SMOKING-BEHAVIOR, European journal of pharmacology. Environmental toxicology and pharmacology section, 248(4), 1993, pp. 333-335
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy",Toxicology
Journal title
European journal of pharmacology. Environmental toxicology and pharmacology section → ACNP
ISSN journal
09266917
Volume
248
Issue
4
Year of publication
1993
Pages
333 - 335
Database
ISI
SICI code
0926-6917(1993)248:4<333:NOAAI->2.0.ZU;2-H
Abstract
Nicotine produced antinociception in mice which was antagonized noncom petetively by naloxone. In addition, at significantly lower doses, nic otine noncompetitively antagonized morphine-induced antinociception. A speculative suggestion regarding the opiatergic and anti-opiatergic a ctions of nicotine is that it significantly promotes and maintains smo king behavior.