ABSTRACTION OF DEUTERIUM FROM DIDEUTEROGLYCINE BY ARYL RADICAL - A MODEL FOR 1,4-BENZENE DIRADICAL REACTIONS WITH PROTEINS

Authors
BRASLAU R ANDERSON MO
Citation
R. Braslau et Mo. Anderson, ABSTRACTION OF DEUTERIUM FROM DIDEUTEROGLYCINE BY ARYL RADICAL - A MODEL FOR 1,4-BENZENE DIRADICAL REACTIONS WITH PROTEINS, Tetrahedron letters, 39(24), 1998, pp. 4227-4230
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
24
Year of publication
1998
Pages
4227 - 4230
Database
ISI
SICI code
0040-4039(1998)39:24<4227:AODFDB>2.0.ZU;2-J
Abstract
Aryl radicals are generated by oxidation of aryl hydrazine with PbO2 o r via photolysis of aryl iodide. Abstraction of deuterium from dideute roglycine derivatives is demonstrated as a model for the possible reac tion of 1,4-aryl diradicals with amino acid residues in proteins. (C) 1998 Elsevier Science Ltd. All rights reserved.