METHYLENIMINIUM SALTS AS ACYLATING AGENT - ONE-STEP SYNTHESIS OF BACCATIN-III FROM 10-DEACETYLBACCATIN-III WITH HIGH SELECTIVITY

Authors
CRAVALLEE C DIDIER E PECQUET P
Citation
C. Cravallee et al., METHYLENIMINIUM SALTS AS ACYLATING AGENT - ONE-STEP SYNTHESIS OF BACCATIN-III FROM 10-DEACETYLBACCATIN-III WITH HIGH SELECTIVITY, Tetrahedron letters, 39(24), 1998, pp. 4263-4266
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
24
Year of publication
1998
Pages
4263 - 4266
Database
ISI
SICI code
0040-4039(1998)39:24<4263:MSAAA->2.0.ZU;2-7
Abstract
New methyleniminium salts were investigated as acylating agent of 10-d eacetylbaccatin III. Thus, synthesis of baccatin III was performed in one step with 79% isolated yield and 98% selectivity using the iminium salt prepared from mesyl chloride and N-ethylacetamide. (C) 1998 Else vier Science Ltd. All rights reserved.