ENANTIOSELECTIVE TOTAL SYNTHESIS OF THE ANTIFUNGAL DILACTONE, UK-2A -THE DETERMINATION OF THE RELATIVE AND ABSOLUTE-CONFIGURATIONS

Authors
SHIMANO M SHIBATA T KAMEI N
Citation
M. Shimano et al., ENANTIOSELECTIVE TOTAL SYNTHESIS OF THE ANTIFUNGAL DILACTONE, UK-2A -THE DETERMINATION OF THE RELATIVE AND ABSOLUTE-CONFIGURATIONS, Tetrahedron letters, 39(24), 1998, pp. 4363-4366
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
24
Year of publication
1998
Pages
4363 - 4366
Database
ISI
SICI code
0040-4039(1998)39:24<4363:ETSOTA>2.0.ZU;2-A
Abstract
The synthesis of the antifungal dilactone, UK-2A, is described. In add ition to providing a workable synthetic route to this potent antifunga l antibiotic, this has allowed us to determine the assignment of the r elative and absolute configurations in the nine-membered ring. (C) 199 8 Elsevier Science Ltd. All rights reserved.