TETRANUCLEOTIDE STR SYSTEM D8S1132 - SEQUENCING DATA AND POPULATION GENETIC COMPARISONS

In the present investigation of the D8S1132 locus 31 selected alleles were sequenced. In total there were 9 distinguishable alleles found to increase in size by regular 4 bp increments from 134 to 170 bp with a repeat array following the pattern (TCTA)(n) TCA (TCTA)(n). One-third of the sequenced alleles exhibited an altered repeat sequence TCTG TC TA at the 3' flanking region of the repeat array. A nomenclature for t he designation of D8S1132 alleles is proposed on the basis of this seq uence data and in accordance with the ISFH recommendations. The allele distribution of the D8S1132 locus has been investigated in three Germ an populations (Halle-, Munster-, and Wiesbaden area) with frequencies ranging from 0.004 to 0.24. No deviation from Hardy-Weinberg equilibr ium could be observed. The heterozygosity was 0.83 and the discriminat ion power 0.96 for the Halle population.