CAR CRASH AFTER MASSIVE INGESTION OF DIGOXIN AND MIDAZOLAM

In a case where a 32-year-old man lost control of his vehicle, urine a nd blood samples were taken 6 h after the crash for toxicological inve stigations. In the hospital, the driver admitted consumption of some d rugs, in particular digoxin and midazolam just before the crash which corresponded to the results of blood analyses. Toxicological findings indicated the presence of digoxin at 12.9 ng/ml and midazolam at 7 ng/ ml in the blood. These results suggested that at the moment of the cra sh digoxin and midazolam blood levels were in the range of toxic and t herapeutic concentrations, respectively. Therefore the respective role s of the drugs in the impairment of the ability to drive at the moment of the crash is discussed.