Y-CHROMOSOME POLYMORPHISMS AND HAPLOTYPES IN WEST SAXONY (GERMANY)

In order to apply a set of useful and high polymorphic Y-STRs in pater nity testing, we performed a population genetic study from Saxony. The allele distributions of the systems DYS19, DYS385, DYS389I/II and DYS 390 were investigated in a sample of 250 unrelated males from the area of Leipzig, PCR products were detected using native polyacrylamide ge l electrophoresis as well as capillary electrophoresis and GenScan Sof tware on the ABI Prism 310 DNA sequencer. Haplotype frequency data of 164 different types were obtained which show that these four systems a re very useful for special cases of paternity and forensic stain analy sis. In addition several confirmed father-son pairs were examined usin g the paternity cases of the institute. One mutation was found in the system DYS390 and sequencing data are presented.