SYNTHESIS OF 1,2,4-TRIAZOLE, 1,3,4-THIADIAZOLE AND 1,3,4-OXADIAZOLE DERIVATIVES OF 6-NITROBENZIMIDAZOLE

Authors
XU PF YANG YP WU SZ ZHANG ZY
Citation
Pf. Xu et al., SYNTHESIS OF 1,2,4-TRIAZOLE, 1,3,4-THIADIAZOLE AND 1,3,4-OXADIAZOLE DERIVATIVES OF 6-NITROBENZIMIDAZOLE, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 37(2), 1998, pp. 127-131
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
37
Issue
2
Year of publication
1998
Pages
127 - 131
Database
ISI
SICI code
0376-4699(1998)37:2<127:SO11A1>2.0.ZU;2-Q
Abstract
A series of new -(6'-nitrobenzimidazole-1-ylmethyl-1,2,4-triazoles 5, 8, 1,3,4-thiadiazole 9, and 1, 3, 4-oxadiazole 10 has been synthesized from 6-nitrobenzimidazole I via ole-1-carbonylmethyl)-4-phenyl-3-thio semicarbazide 6. The thiosemicarbazides have been readily obtained fro m 6-nitrobenzimidazole-1-acetic acid hydrazide 3 in good yield. These compounds have been characterized on the basis of elemental analyses, IR, NMR and MS.