Ms. Amine et Mmh. Arief, UTILITIES OF SACCHARINYL ACETYL ISOTHIOCYANATE IN SYNTHESIS OF NON-CONDENSED POLYNUCLEAR HETEROCYCLIC-COMPOUNDS OF EXPECTED BIOLOGICAL-ACTIVITY, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 37(2), 1998, pp. 135-138
The title compound 1 has been reacted with nitrogen nucleophiles pheny
lhydrazine, acetylhydrazines, benzoylhydrazine, sodium azide, anthrani
lic acid and oxygen nucleophile as o-aminophenol, and amino acid as gl
ycine. Also the reaction of 1 with phenyl isocyanate and active methyl
ene compounds has been investigated and it was found that all these re
actions proceeds via isothiocyanate heterocyclization to furnish non-c
ondensed heterocyclic compounds 2-14.