I. Ayan et al., GRANULOCYTIC SARCOMA IN THE DIFFERENTIAL-DIAGNOSIS OF SMALL ROUND-CELL TUMOR OF CHILDHOOD - A CASE-REPORT, International journal of pediatric hematology/oncology, 5(1), 1998, pp. 29-34
The diagnosis of granulocytic sarcoma has frequently been a problem fo
r the pathologist because of the immature nature of the tumor. One oth
er group of difficult-to-diagnose tumors is the small round cell tumor
s of childhood, which lack any particular morphologic feature that wou
ld allow a precise diagnosis. This report describes a 9-month-old boy
with a soft tissue mass on the left ankle initially diagnosed as small
round cell malignant tumor, who 2 months from diagnosis developed ano
ther tumor simultaneously with the blood and bone marrow manifestation
s of acute nonlymphocytic leukemia. Following leukemic manifestation,
the retrospective diagnosis of granulocytic sarcoma was made. It is su
ggested that granulocytic sarcoma should be included in the differenti
al diagnosis of small round cell tumors in children.