L. Tischendorf et al., CHANCE AND RISK OF CONTROLLING RABIES IN LARGE-SCALE AND LONG-TERM IMMUNIZED FOX POPULATIONS, Proceedings - Royal Society. Biological Sciences, 265(1399), 1998, pp. 839-846
The large-scale immunization of European fox populations against rabie
s is currently under the microscope for reducing the considerable expe
nditure without putting public health at risk. Empirical knowledge is
inadequate to interpret the lasting sporadic incidences and, therefore
, to verify the final success of the immunization campaigns. By using
a proven simulation model we show that rabies can persist on a very lo
w level in the form of spatio-temporal moving infection clusters withi
n a highly immunized fox population. We found further: (i) the existen
ce of a threshold after which the chance of eradicating the disease by
vaccination increases clearly and (ii) that at least six years of 70%
mean immunization race are required to guarantee a likely success.