Le. Allen et al., THE ASSOCIATION BETWEEN THE OCULOCARDIAC REFLEX AND POSTOPERATIVE VOMITING IN CHILDREN UNDERGOING STRABISMUS SURGERY, Eye, 12, 1998, pp. 193-196
The oculocardiac reflex (OCR) is a potentially serious complication of
ophthalmic surgery which is most commonly elicited during paediatric
strabismus surgery. Post-operative vomiting (POV) is also extremely co
mmon after such procedures and may result in admission following plann
ed day-case surgery. Although many factors play a part in the occurren
ce of POV, stimulation of the trigemino-vagal reflex are is thought to
explain the particularly high rate of vomiting after strabismus surge
ry. The OCR and the vaso-vagal response share this neuronal pathway, t
he bradycardia of the OCR often being the only objective feature of th
e vaso-vagal response while the patient is anaesthetised. The aim of t
his study was to investigate the possible association between the occu
rrence of the OCR and subsequent POV in children undergoing strabismus
surgery. We have studied this relationship in 79 children, aged betwe
en 1 and 13 years, undergoing strabismus surgery under standardised an
aesthetic conditions. A positive OCR was regarded as a drop in heart r
ate of 10% or more, or the onset of a dysrhythmia. An intraoperative O
CR was elicited in 51 (64.6%) of the 79 children, whilst 29 (36.7%) de
veloped POV in the subsequent 24 h period. There was a significant ass
ociation between a positive intraoperative OCR and POV (p = 0.01): chi
ldren with a positive OCR were 2.6 times more likely to vomit than tho
se without the reflex. We conclude that there is an association betwee
n the occurrence of the OCR and POV and discuss possible preventive st
rategies.