In temperate latitudes, ewes exhibit great seasonal variation in repro
ductive activity. Changes in daylength are responsible for the seasona
lity of reproduction. The photoperiodic control of ovarian cyclicity i
nvolves the regulation of pulsatile luteinizing hormone (LH) secretion
. The annual variations of daylength are encoded by the pineal gland i
nto a circadian secretion of melatonin which in turn drives the activi
ty of the hypothalamohypophyseal axis. Among the neuronal systems invo
lved in the seasonal control of LH secretion, the dopaminergic A15 nuc
leus appears as an essential link in the cascade of events leading to
the inhibition of LH secretion during anoestrus.