EFFECT OF THROMBOXANE SYNTHETASE INHIBITOR ON FELINE INFECTIOUS PERITONITIS IN CATS

Two cats with abdominal effusion and anorexia were diagnosed as feline infectious peritonitis (FIP). We tried to evaluate the effect of thro mboxane (Tx) synthetase inhibitor, ozagrel hydrochloride, on the progr ession of symptoms and clinicopathologic data characteristic to FIP. A fter administration of Tx synthetase inhibitor, improvement of appetit e and activity, decreases of peritoneal effusion reduction of leukocyt e number to normal level, and improvement of hunger gamma-globulinemia were found in 2 cats with FIP. These findings suggest that the vascul itis in FIP can be successfully treated with Tx synthetase inhibitor w hich inhibits platelet aggregation.