The purpose of this study was to reveal patterns of association among
seven types of dental anomalies (aplasia of second premolars, small si
ze of maxillary lateral incisors, infraocclusion of primary molars, en
amel hypoplasia, ectopic eruption of first molars, supernumerary teeth
, and palatal displacement of maxillary canines) in an untreated ortho
dontic population, ages 7 to 14. The prevalence of associated tooth an
omalies in seven groups of 100 subjects selected according to one prim
arily diagnosed dental anomaly was compared with the prevalence of the
examined dental anomalies in a control group of 1,000 subjects. Signi
ficant reciprocal associations (p<0.005) were found among five of the
anomalies (aplasia of second premolars, small size of maxillary latera
l incisors, infraocclusion of primary molars, enamel hypoplasia, and p
alatal displacement of maxillary canines), suggesting a common genetic
origin for these conditions. Supernumerary teeth appeared to be a sep
arate etiological entity with respect to all other examined tooth anom
alies. The existence of associations between different tooth anomalies
is clinically relevant, as the early diagnosis of one anomaly may ind
icate an increased risk for others.