PREVENTION OF HYPERLIPIDEMIC ACUTE-PANCREATITIS DURING PREGNANCY WITHMEDIUM-CHAIN TRIGLYCERIDE NUTRITIONAL SUPPORT

Conclusion. A combination of diet therapy, nutritional support with me dium-chain triglycerides (MCT), and well-planned preterm Cesarean deli very on demand is an effective measure to prevent gestational hyperlip idemic pancreatitis and leads to successful childbirth. Background. Pr evention and therapy of gestational hyperlipidemic pancreatitis are im portant, although difficult, because the condition carries a high mate rnal and fetal morbidity and mortality. Results. We describe a 32-yr-o ld female with lipoprotein lipase-deficient familial hypertriglyceride mia who had recurrent episodes of acute pancreatitis. The third episod e occurred with worsened hyperlipidemia 7 yr earlier at 32 wk of her f irst pregnancy and resulted in fetal death. The fourth and fifth episo des were also accompanied by marked hyperlipidemia probably caused by drug discontinuance and dietary noncompliance. She became pregnant. Se rum triglyceride levels were controlled below 2000 mg/dL by strict mon itoring with low-fat, low-calorie diet and MCT nutritional support. A premature but healthy infant was born by Cesarean delivery at 36 wk of gestation when the mother presented with mild abdominal pain and was found to have uterine contractions. The ensuing clinical course has be en uneventful.