Objective. Granuloma annulare is an uncommon benign inflammatory derma
tosis characterized by the formation of dermal papules with a tendency
to form rings. There are several clinically distinct forms. The subcu
taneous form is the most frequently encountered by radiologists, with
the lesion presenting as a superficial mass. There are only a few scat
tered reports of the imaging appearance of this entity in the literatu
re. We report the radiologic appearance of five cases of subcutaneous
granuloma annulare. Design and patients. The radiologic images of five
patients (three male, two female) with subcutaneous granuloma annular
e were retrospectively studied. Mean patient age was 6.4 years (range,
2-13 years). The lesions occurred in the lower leg (two), foot, forea
rm, and hand. MR images were available for all lesions, gadolinium-enh
anced imaging in three cases, radiographs in four, and bone scintigrap
hy in one. Results. Radiographs showed unmineralized nodular masses lo
calized to the subcutaneous adipose tissue. The size range, in greates
t dimension on imaging studies, was 1-4 cm. MR images show a mass with
relatively decreased signal intensity on all pulse sequences, with va
riable but generally relatively well defined margins. There was extens
ive diffuse enhancement following gadolinium administration. Conclusio
n. The radiologic appearance of subcutaneous granuloma annulare is cha
racteristic, typically demonstrating a nodular soft-tissue mass involv
ing the subcutaneous adipose tissue. MR images show a mass with relati
vely decreased signal intensity on all pulse sequences and variable bu
t generally well defined margins. There is extensive diffuse enhanceme
nt following gadolinium administration. Radiographs show a soft-tissue
mass or soft-tissue swelling without evidence of bone involvement or
mineralization. This radiologic appearance in a young individual is hi
ghly suggestive of subcutaneous granuloma annulare.