An algorithm for correction of the geometrical distortion in digital s
ubtraction angiography (DSA) images was developed. Originally invented
for 3D X-ray angiography, the algorithm was implemented in a computer
program designed to fulfil the specific needs of stereotaxic DSA. The
algorithm is based on transformation of an image of a grid from a dis
torted image back into its original pattern. The same transformation i
s then applied pixel-by-pixel to the angiographic images, which are ac
quired in direct conjunction with the grid image, without moving the g
antry. The algorithm was tested in phantom studies and in the clinical
situation with seven patients in ten examinations. Comparisons were m
ade between co-ordinate determinations made on conventional full-size
cut film and those performed on uncorrected and corrected DSA images,
using 30- and 23-cm fields of view. With our method of measurement we
could not show any remaining geometric distortion in the corrected DSA
images. This distortion correction can, if properly applied, be used
for high-precision stereotaxic DSA.