Peri-operative silent myocardial ischaemia in patients undergoing lower limb joint replacement surgery: an indicator of postoperative morbidity or mortality
Gwg. French et al., Peri-operative silent myocardial ischaemia in patients undergoing lower limb joint replacement surgery: an indicator of postoperative morbidity or mortality, ANAESTHESIA, 54(3), 1999, pp. 235-240
Citations number
26
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
One hundred and twenty-seven patients undergoing major lower limb joint rep
lacement surgery were studied to determine the incidence of silent myocardi
al ischaemia and to ascertain any link between pre-operative cardiac risk f
actors, silent myocardial ischaemia and postoperative morbidity. Patients u
nderwent ambulatory ECG monitoring for 4 days (on the pre-operative night a
nd for 3 days postoperatively). Postoperative cardiorespiratory symptomatol
ogy and morbidity was assessed by questionnaire at 3 months. Eighty-seven p
atients had risk factors for silent myocardial ischaemia; 42 patients (30 w
ith risk factors) had peri-operative silent myocardial ischaemia. The media
n ischaemic loads (range) were 1.04 (0.32-13.31) min.h(-1) pre-operatively
and 5.53 (0.26-56.39), 6.69 (0.04-42.71) and 1.23 (0.1-53.74) min.h(-1) on
postoperative days 1-3, respectively. Risk factors did not predict the occu
rrence of silent myocardial ischaemia or an increased ischaemic load pre-op
eratively or overall postoperatively. New symptoms (chest pain, palpitation
s, breathlessness or fatigue) were associated with both silent myocardial i
schaemia and ischaemic load (p < 0.05). Thus cardiac risk factors do not pr
edict the occurrence of silent myocardial ischaemia or adverse outcome. Per
i-operative silent myocardial ischaemia was associated with increased posto
perative fatigue.