In the first half of pregnancy the well-known occurrence of glycogen incorp
oration in the supra- and infranuclear cytoplasm of the villous enterocytes
was verified. This enormous glycan store is evidently of very little funct
ional importance. It seems to be an expression of a disordered glycogenolys
is. These masses of glycogen are incorporated into impressive glycogenosome
s, which are the predominante cytoplasmic inclusions for a short period of
time. According to the present results it is not certain whether lysosomal
glycogenolysis happens. There is no morphological or functional evidence fo
r a utilization og glycogen.