Study on the distribution of radioactive trace elements in vitamin D-overloaded rats using the multitracer technique

The uptake and distribution of radioisotopes of beryllium, calcium, scandiu m, vanadium, chromium, manganese, iron, cobalt, nickel, zinc, gallium, arse nic, strontium and barium in vitamin D (VD)-overloaded rats were investigat ed and compared with those in control rats, using the multitracer technique . Each element revealed its characteristic distribution among various organ s in control and VD-overloaded rats. For some elements, such as cobalt and chromium, the distribution patterns in them were significantly different. T hese results are discussed in terms of the metabolism of the elements in ra ts. (C) 1999 Elsevier Science Ltd. All rights reserved.