Dyschromatosis symmetrica hereditaria (reticulate acropigmentation of Dohi): report of a Japanese family with the condition and a literature review of 185 cases
M. Oyama et al., Dyschromatosis symmetrica hereditaria (reticulate acropigmentation of Dohi): report of a Japanese family with the condition and a literature review of 185 cases, BR J DERM, 140(3), 1999, pp. 491-496
We report a Japanese family with dyschromatosis symmetrica hereditaria (DSH
) (MIM 127400 in McKusick's Mendelian Inheritance in Man), a rare autosomal
dominant genodermatosis, predominantly occurring among Japanese and Korean
individuals. Members of the present family affected with the disease showe
d a mixture of hyperpigmented and hypopigmented macules distributed on the
face and the dorsal aspects of the extremities, which are typical of DSH, A
s most of the literature on DSH has been written in Japanese, dermatologist
s outside Japan are not familiar with the condition, In this paper, 185 cas
es of DSH, most of them reported in Japanese, are reviewed and unique clini
cal, histological and genetic features of this condition are delineated.