A prospective placebo controlled double blind randomised study to investigate the use of indoramin to prevent post-operative voiding disorders after surgical treatment for genuine stress incontinence

Citation
Ajs. Watson et al., A prospective placebo controlled double blind randomised study to investigate the use of indoramin to prevent post-operative voiding disorders after surgical treatment for genuine stress incontinence, BR J OBST G, 106(3), 1999, pp. 270-272
Citations number
7
Categorie Soggetti
Reproductive Medicine","da verificare
Journal title
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
ISSN journal
14700328 → ACNP
Volume
106
Issue
3
Year of publication
1999
Pages
270 - 272
Database
ISI
SICI code
1470-0328(199903)106:3<270:APPCDB>2.0.ZU;2-1
Abstract
A prospective placebo controlled double blind randomised study was undertak en to investigate the use of indoramin an alpha blocker to prevent post-ope rative voidine disorders after surgical treatment for genuine stress incont inence. Fifty-six patients were randomised to receive indoramin 20 mg orall y twice a day or identical placebo from the first post-operative day until discharge from hospital. After seven exclusions, 49 patients were included in the study. There was no significant difference between the treatment (in doramin) group and placebo group for any of the outcomes measured. The rout ine use of indoramin to prevent post-operative voiding problems cannot be j ustified on the basis of these data.