Crystal structures of highly stabilized ylides: methyl(3-methoxy,2-methoxycarbonylbenzoyl)tri-phenylphosphoranylideneacetate and methyl(2-methoxycarbonyl,6-nitrobenzoyl)triphenylphosphoranylideneacetate and the salt methyl(triphenylphosphoranylidene)acetate tetrafluoroborate
Fd. Rochon et al., Crystal structures of highly stabilized ylides: methyl(3-methoxy,2-methoxycarbonylbenzoyl)tri-phenylphosphoranylideneacetate and methyl(2-methoxycarbonyl,6-nitrobenzoyl)triphenylphosphoranylideneacetate and the salt methyl(triphenylphosphoranylidene)acetate tetrafluoroborate, CAN J CHEM, 76(12), 1998, pp. 1844-1852
Citations number
20
Categorie Soggetti
Chemistry
Journal title
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE
At lower temperatures stabilized ylides react with unsymmetrically substitu
ted phthalic anhydrides to give two acyclic adducts. When the reactions are
allowed to proceed at higher temperature enol lactones are formed. Identif
ication of the acyclic intermediates was necessary to understand the mechan
ism of these Wittig reactions. The transient species trapped in the reactio
n with trimethyloxonium tetrafluoroborate were unambiguously identified by
crystallographic methods. The crystal structures of the tetrafluoroborate s
alt of methyl(triphenylphosphoranylidene)-acetate (8), methyl(3-methoxy,2-m
ethoxycarbonylbenzoyl)triphenylphosphoranylideneacetate (6 beta), and methy
l(2-methoxycarbonyl,6-nitrobenzoyl)triphenylphosphoranylideneacetate (7 alp
ha) were studied by X-ray diffraction. The ionic salt (8) is monoclinic, P2
(1)/c, a = 12.640(5), b = 13.945(9), c = 14.825(6) Angstrom, beta = 125.32(
3)degrees, Z = 4, and R = 0.065 (F > 5.4 sigma(F)). Crystal 6 beta is monoc
linic, P2(1)/c, a = 16.391(16), b = 9.029(6), c = 19.835(19) Angstrom, beta
= 116.60(6)degrees Z = 4, and R = 0.070 (F > 4.6 sigma(F)), while crystal
7 alpha is also monoclinic, P2(1)/c, a = 9.513(5), b = 9.361(3), c = 30.908
(13) Angstrom, beta = 98.42(3)degrees, Z = 4, and R = 0.057 (F > 5 sigma(F)
). In the BF4- salt (12), the four P-C distances are equal (1.791(5)-1.801(
7) Angstrom) with identical tetrahedral angles. For the two triphenylphosph
oranylideneacetate compounds, the fourth P-C(1) bond is shorter (1.762(6)-1
.734(5) Angstrom) than the three P-C(Ph) bonds (avg. 1.809(5) Angstrom). Th
e angles C(1)-P-C(Ph) are also larger (avg. 112.9(2)degrees for 6 beta and
111.9(2)degrees for 7 alpha) than the C(Ph)-P-C(Ph) angles (avg. 105.8(2)de
grees for 6 beta and 106.9(2)degrees for 7 alpha). These values suggest a m
ultiple nature for the P-C(1) bond. In the nitro derivative, the nitro and
the ester groups are disordered equally in positions 2 and 6.