The self-energies of quasinucleon states in nuclear matter are investi
gated using a finite-density QCD sum-rule approach developed previousl
y. The sum rules are obtained for a general QCD interpolating field fo
r the nucleon. The key phenomenological inputs are the nucleon sigma t
erm, the strangeness content of the nucleon, and quark and gluon distr
ibution functions deduced from deep-inelastic scattering. The emphasis
is on testing the sensitivity and stability of sum-rule predictions t
o variations of the condensates and other input parameters. At nuclear
matter saturation density, the Lorentz vector self-energy is found to
be positive with a magnitude of a few hundred MeV, which is comparabl
e to that suggested by relativistic nuclear phenomenology This result
is quite stable. The prediction for the scalar self-energy is very sen
sitive to the undetermined values of the in-medium four-quark condensa
tes.