Techniques for skull base surgery have become well established over the las
t 10 years. Most of these techniques are used in adult patients for skull b
ase tumors and neurovascular diseases. There are very few large series of p
ediatric patients in whom skull base approaches have been used, because of
the rarity of these conditions. The authors would like to present a relativ
ely large series of 26 pediatric patients who underwent skull base approach
es for tumor resection. These tumors involved the anterior cranial base in
5 patients, the medial cranial skull base in 4 patients, and the posterior
cranial base in 12 cases. Five patients had tumors that involved two or mor
e fossae. The overall complication rate was 57%, which included temporary c
ranial nerve palsies, CSF leak and infection. Patients with permanent compl
ications were 8 in number (37%). There was 1 postoperative death from pneum
onia approximately 6 weeks after surgery. Complete tumor removal was achiev
ed in 24 of the 26 patients. Skull base tumors in children are often extens
ive and present significant surgical challenges. Although complete tumor ex
tirpation is the goal in most pediatric patients, this is often achieved on
ly with some morbidity. This paper demonstrates the effectiveness of skull
base approaches for these tumors and underscores the high stakes involved.