The influence of chlorine on the activities of lactate dehydrogenase and its isoenzymes in plasma of lambs

The influence of chlorine doses in drinking water on the activities of lact ate dehydrogenase and its isoenzymes in blood plasma of ewe lambs was studi ed after short-term and long-term chlorine action. Drinking water was treat ed with chlorine gas and adjusted with preparation Save-Super in such a way that it contained 0.3 mg active chlorine/l at the time of administration. We also used a medication of chlortetracycline-chloride (preparation Aureov it 12 C 80 ply. a. u, v.), added to the feed mixture to ensure consumption of the preparation 0.35 g/kg 1.w./day. The short-term action of chlorine co ncentrations showed no significant differences in the total LD activity and LD isoenzymes between the control and the experimental groups. However, si gnificant difference in the activity of isoenzyme LDI (P < 0.05) was observ ed at one sampling in the experimental group treated with Aureovit after th e 3-months exposure.