Ch. Dunphy, Natural killer cell lymphoma of the small intestine: Diagnosis by flow cytometric immunophenotyping of paracentesis fluid, DIAGN CYTOP, 20(4), 1999, pp. 246-248
Natural killer (NK) cell lymphoma is a mass-forming neoplasm of putative NK
cell lineage that typically appears in extranodal locations and has the fo
llowing immunophenotype: CD2 positive. surface CD3 negative, cytoplasmic CD
3 positive, and CD56 positive. We report a case of small-intestinal NK cell
lymphoma that was originally diagnosed as an enteropathy-associated T-cell
lymphoma based on paraffin immunohistochemistry;. However subsequent flow
cytometric immunophenotyping of paracentesis fluid resulted in the correct
diagnosis. We describe the case to illustrate the usefulness of this techni
que, which has not previously been described in such a case. (C) 1999 Wiley
-Liss, Inc.