Flow cytometry: a versatile tool for all phases of drug discovery

Authors
Nolan, JP Lauer, S Prossnitz, ER Sklar, LA
Citation
Jp. Nolan et al., Flow cytometry: a versatile tool for all phases of drug discovery, DRUG DISC T, 4(4), 1999, pp. 173-180
Citations number
49
Categorie Soggetti
Pharmacology & Toxicology
Journal title
DRUG DISCOVERY TODAY
ISSN journal
13596446 → ACNP
Volume
4
Issue
4
Year of publication
1999
Pages
173 - 180
Database
ISI
SICI code
1359-6446(199904)4:4<173:FCAVTF>2.0.ZU;2-H
Abstract
The applications of flow cytometry are being extended beyond cells into mol ecular interactions and genomic analyses. The authors explain how instrumen tation and reagent development are combining to improve flow cytometric thr oughput by orders of magnitude beyond that possible just a few years ago, s uch that the combination of sensitivity, throughput and versatility makes f low cytometry an analytical platform with applications at all stages of dru g discovery.