Proteomics: a major new technology for the drug discovery process

Proteomics is a new enabling technology that is being integrated into the d rug discovery process. This will facilitate the systematic analysis of prot eins across any biological system or disease, forwarding new targets and in formation on mode of action, toxicology and surrogate markers, Proteomics i s highly complementary to genomic approaches in the drug discovery process and, for the first time, offers scientists the ability to integrate informa tion from the genome, expressed mRNAs, their respective proteins and subcel lular localization. It is expected that this will lead to important new ins ights into disease mechanisms and improved drug discovery strategies to pro duce novel therapeutics.