Objective: Intentional puncture of the membrane has been reported to be a p
romising new method for the management of twin-twin transfusion syndrome. C
ase Report: Treatment of twin-twin transfusion syndrome with serial amnioce
nteses resulted in unintentional puncture of the dividing membrane at 24 we
eks of gestation. Fetal growth discordance increased, and twin-twin transfu
sion did not improve following the puncture. Intrauterine death of both fet
uses at 27 weeks of gestation occurred, Conclusion: Amniotic septostomy for
the treatment of twin-twin transfusion sydnrome should be performed with s
erious consideration.