Objective: To study the fertility potential of individual semen donors with
ejaculates of optimal as compared to suboptimal quality. Methods: 363 seme
n donations were obtained from 11 donors between January 1993 and September
1997. 270 samples were cryopreserved and 1,399 straws obtained from 120 ej
aculates were used in 495 insemination cycles. Results: 52 pregnancies were
achieved in 128 recipients (40.6%). No significant differences were found
between donors of high fecundability and those of low fecundability regardi
ng sperm parameters. The mean donor fecundability index was 10.5%. The opti
mal and suboptimal samples yielded similar results. Donors with suboptimal
semen quality had an increased number of samples rejected after thawing. Co
nclusion: Traditional semen analysis parameters do not differentiate high f
rom low fecundability donors. Suboptimal results of the semen analysis shou
ld not exclude potential donors from an artificial insemination donor (AID)
program.