Phosphorylcholine: friend or foe of the immune system?

Authors
Harnett, W Harnett, MM
Citation
W. Harnett et Mm. Harnett, Phosphorylcholine: friend or foe of the immune system?, IMMUNOL TOD, 20(3), 1999, pp. 125-129
Citations number
59
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
20
Issue
3
Year of publication
1999
Pages
125 - 129
Database
ISI
SICI code
0167-5699(199903)20:3<125:PFOFOT>2.0.ZU;2-4
Abstract
Phosphorylcholine (PC) is a structural component of a variety of prokaryoti c and eukaryotic pathogens. In some cases, PC in infectious agents can bene fit the infected host due to its targeting by both the innate and adaptive immune responses. However, as discussed here, PC exhibits a surprising rang e of immunomodulatory properties that might be to the detriment of the host .