On the intrathymic intercellular transfer of self-determinants

Authors
Viret, C Barlow, AK Janeway, CA
Citation
C. Viret et al., On the intrathymic intercellular transfer of self-determinants, IMMUNOL TOD, 20(1), 1999, pp. 8-10
Citations number
20
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
20
Issue
1
Year of publication
1999
Pages
8 - 10
Database
ISI
SICI code
0167-5699(199901)20:1<8:OTIITO>2.0.ZU;2-J
Abstract
Intercellular transfer of self-determinants within the thymic microenvironm ent is likely to improve the establishment of central T-cell tolerance. Rec ent observations suggest that such transfer can involve direct displacement of major histocompatibility complex (MHC)bound peptides.