Enhancing the inhibitory effect of nicotinamide upon collagen II induced arthritis in mice using N-acetylcysteine

Authors
Kroger, H Hauschild, A Ohde, M Bache, K Voigt, WP Ehrlich, W
Citation
H. Kroger et al., Enhancing the inhibitory effect of nicotinamide upon collagen II induced arthritis in mice using N-acetylcysteine, INFLAMMATIO, 23(2), 1999, pp. 111-115
Citations number
9
Categorie Soggetti
Immunology
Journal title
INFLAMMATION
ISSN journal
03603997 → ACNP
Volume
23
Issue
2
Year of publication
1999
Pages
111 - 115
Database
ISI
SICI code
0360-3997(199904)23:2<111:ETIEON>2.0.ZU;2-M
Abstract
We could show that both nicotinamide and N-acetylcysteine inhibit collagen induced arthritis in mice. In the present paper, using lower doses of each, we applied combinations of these two substances. We were able to confirm p otentiating effects of these combinations. These results may allow new pers pectives for the therapy of arthritis to emerge.