PRECISE LOCALIZATION ON CHROMOSOME-12 OF THE ATF-1 GENE BY FLUORESCENCE IN-SITU HYBRIDIZATION

Authors
DESMAZE C ZUCMAN J DELATTRE O MELOT T THOMAS G AURIAS A
Citation
C. Desmaze et al., PRECISE LOCALIZATION ON CHROMOSOME-12 OF THE ATF-1 GENE BY FLUORESCENCE IN-SITU HYBRIDIZATION, Human genetics, 93(2), 1994, pp. 207-208
Citations number
9
Categorie Soggetti
Genetics & Heredity
Journal title
Human genetics → ACNP
ISSN journal
03406717
Volume
93
Issue
2
Year of publication
1994
Pages
207 - 208
Database
ISI
SICI code
0340-6717(1994)93:2<207:PLOCOT>2.0.ZU;2-1
Abstract
The ATF-1 gene encodes for a transcription factor normally regulated b y cAMP (Hai et al. 1989, Yoshimura et al. 1990). Recently, it has been shown to be involved in the recurrent t(12;22) translocation observed in soft tissue malignant melanoma, in a fusion gene with the EWS gene (Zucman et al. 1993). We report here on its precise localization on c hromosome 12 by fluorescence in situ hybridization.