Lo. Svensson et al., SCREENING VOIDED URINE FOR CHLAMYDIA-TRACHOMATIS IN ASYMPTOMATIC ADOLESCENT FEMALES, Acta obstetricia et gynecologica Scandinavica, 73(1), 1994, pp. 63-66
First catch urine (FCU) from 751 asymptomatic adolescent female high s
chool students, with sexual debut, were screened for the presence of C
hlamydia trachomatis (Group A). The prevalence of C. trachomatis infec
tion in Group A was 2.1% (16/751). In Group B, 619 asymptomatic adoles
cent females attending a youth and a family planning clinic were scree
ned for C. trachomatis by testing FCU and cervical specimens. An enzym
e immunoassay (IDEIA-III) was used to detect C. trachomatis vertified
by fluorescein-isothianate-conjugated (FITC) monoclonal antibodies. On
ly samples positive in both tests were regarded as true positive. The
cervical samples from the women in Group B were positive in 7.8% (48/6
19), while the FCU were positive in 6.0% (37/619). Detection of C. tra
chomatis by EIA in FCU samples was found useful for screening females
for genital chlamydial infection. The prevalence of C. trachomatis in
an unselected asymptomatic population was found to be lower than in ag
e-matched individuals seeking medical advice in the same coherent area
.