Clinical practice guidelines (CPGs) for end-stage renal failure (ESRD) were
recently published, and represent a comprehensive review of available lite
rature and the considered judgment of experts in ESRD. To prioritize and im
plement these guidelines, the evidence underlying each guideline should be
ranked and the attributes of each should be defined. Strategies to improve
practice patterns should be tested. Focused information for each high prior
ity guideline should be disseminated, including a synopsis and assessment o
f the underlying evidence, the evidence model used to develop that guidelin
e, and suggested strategies for CPG implementation. Clinical performance me
asures should be developed and used to measure current practice, and the su
ccess of changing practice patterns on clinical outcomes. Individual practi
tioners and dialysis facilities should be encouraged to utilize continuous
quality improvement techniques to put the guidelines into effect. Local imp
lementation should proceed at the same time as a national project to conver
t high priority CPGs into clinical performance measures proceeds. Patients
and patient care organizations should participate in this process, and prof
essional organizations must make a strong commitment to educate clinicians
in the methodology of CPG and performance measure development and the techn
iques of continuous quality improvement. Health care regulators should unde
rstand that CPGs are not standards, but are statements that assist practiti
oners and patients in making decisions.