The medical conditions in which transfusion is required, types of transfusi
ons and host response to transfused cells are different in neonates and inf
ants than in adults. As a result, certain features and complications af tra
nsfusion: are more important. This article explores key aspects of these di
fferences, indications for transfusion therapy, and possible actions blood
banks can, take to improve transfusion safety and efficacy.