Non-secretory solitary plasmacytoma of the spleen

A case of primary nonsecretory plasmacytoma of the spleen is reported. On l aparotomy and splenectomy a 920 g spleen was removed, measuring 16 x 14 x 6 cm. The cut surface of the entire spleen showed that the tumour occupied m ost of the splenic tissue. A bone marrow aspirate and trephine, skeletal su rvey showed no signs of myeloma, Biopsy of the liver and regional lymph nod es was normal. Immunocytochemistry of the splenic tumour showed positivity for pan-B and plasma cell markers. After splenectomy the patient was treate d with chemotherapy according to protocol VBCMP (M2).