Systemic lupus erythematosus associated with primary large cell carcinoma of the lung

The association between systemic lupus erythematosus (SLE) and malignancy h as been controversial in the literature. We report a case of lung cancer in a 50-year-old woman with a 4-year history of SLE. She underwent surgery at a pathological stage of T2N2MO, but she eventually died of rapid recurrenc e of the cancer in the abdomen resulting in massive haemorrhage from the in ferior vena cava (IVC), Immunological disorders related to SLE are thought to contribute to rapid progression of the malignancy.